Human intraepithelial mast cell differentiation and effector function are directed by TGF-β signalin...
Human intraepithelial mast cell differentiation and effector function are directed by TGF-β signaling
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Publisher
Ann Arbor: American Society for Clinical Investigation
Journal title
Language
English
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Publisher
Ann Arbor: American Society for Clinical Investigation
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Contents
Mast cells (MCs) expressing a distinctive protease phenotype (MC 5) selectively expand within the epithelium of human mucosal tissues during type 2 (T2) inflammation. While MC,s are phenotypically distinct from subepithelial MCs (MCs), signals driving human MC, differentiation and this subset's contribution to inflammation remain unexplored. Here,...
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Full title
Human intraepithelial mast cell differentiation and effector function are directed by TGF-β signaling
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TN_cdi_proquest_journals_3161975448
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3161975448
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ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JC1174981.
