Gpnmb Defines a Phagocytic State of Microglia Linked to Neuronal Loss in Prion Disease
Gpnmb Defines a Phagocytic State of Microglia Linked to Neuronal Loss in Prion Disease
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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The reaction of different cell types to prion infections is highly heterogeneous. While neurons experience spine retraction and eventually death, astrocytes and microglia undergo strong activation and proliferation. Here we analyzed the cell-type specific responses to prion diseases by establishing a spatiotemporal transcriptomic atlas of mice infe...
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Gpnmb Defines a Phagocytic State of Microglia Linked to Neuronal Loss in Prion Disease
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TN_cdi_proquest_journals_3165948690
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3165948690
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E-ISSN
2692-8205
DOI
10.1101/2025.02.11.637592
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https://www.proquest.com/docview/3165948690?pq-origsite=primo&accountid=13902
