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Evaluating cell type deconvolution in FFPE breast tissue: application to benign breast disease

Evaluating cell type deconvolution in FFPE breast tissue: application to benign breast disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3168786415

Evaluating cell type deconvolution in FFPE breast tissue: application to benign breast disease

About this item

Full title

Evaluating cell type deconvolution in FFPE breast tissue: application to benign breast disease

Publisher

Oxford: Oxford University Press

Journal title

NAR genomics and bioinformatics, 2024-09, Vol.6 (3)

Language

English

Formats

Publication information

Publisher

Oxford: Oxford University Press

More information

Scope and Contents

Contents

Transcriptome profiling using RNA sequencing (RNA-seq) of bulk formalin-fixed paraffin-embedded (FFPE) tissue blocks is a standard method in biomedical research. However, when used on tissues with diverse cell type compositions, it yields averaged gene expression profiles, complicating biomarker identification due to variations in cell proportions....

Alternative Titles

Full title

Evaluating cell type deconvolution in FFPE breast tissue: application to benign breast disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_3168786415

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3168786415

Other Identifiers

ISSN

2631-9268

E-ISSN

2631-9268

DOI

10.1093/nargab/lqae098

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