BIOACTIVE INTERLEUKIN-1 DETECTED IN IBD PATIENT INTESTINAL BIOPSIES IS A HALLMARK OF ULCERS AND CORR...
BIOACTIVE INTERLEUKIN-1 DETECTED IN IBD PATIENT INTESTINAL BIOPSIES IS A HALLMARK OF ULCERS AND CORRELATES WITH TRANSCRIPTOMIC ASSESSMENTS, INCLUDING AN ULCER-ASSOCIATED GENE MODULE
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Author / Creator
Losa, Marco , Field, Michael , Collen, Lauren , Barends, Jared , Ringel, Amit , Bresnahan, Mairead , Yang, Jessica , Tumminkatti, Rhea , Sveen, Mia , Bearup, Richelle , Kotlarz, Daniel , Klein, Christoph , Argmann, Carmen , Schadt, Eric , Muise, Aleixo , Thiagarajah, Jay , Eran, Alal , Horwitz, Bruce , Snapper, Scott and Mitsialis, Vanessa
Publisher
US: Oxford University Press
Journal title
Language
English
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Publisher
US: Oxford University Press
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Contents
Abstract
BACKGROUND
Interleukin (IL)-1 and its post-translationally modified and released forms, IL-1α and IL-1β, have been identified as key molecules to maintain mucosal homeostasis and to drive inflammatory bowel disease (IBD). Deep cellular phenotypic, transcriptional, and in vitro data highlight the importance of IL-1-associated cytokine...
Alternative Titles
Full title
BIOACTIVE INTERLEUKIN-1 DETECTED IN IBD PATIENT INTESTINAL BIOPSIES IS A HALLMARK OF ULCERS AND CORRELATES WITH TRANSCRIPTOMIC ASSESSMENTS, INCLUDING AN ULCER-ASSOCIATED GENE MODULE
Authors, Artists and Contributors
Author / Creator
Field, Michael
Collen, Lauren
Barends, Jared
Ringel, Amit
Bresnahan, Mairead
Yang, Jessica
Tumminkatti, Rhea
Sveen, Mia
Bearup, Richelle
Kotlarz, Daniel
Klein, Christoph
Argmann, Carmen
Schadt, Eric
Muise, Aleixo
Thiagarajah, Jay
Eran, Alal
Horwitz, Bruce
Snapper, Scott
Mitsialis, Vanessa
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_3169882133
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3169882133
Other Identifiers
ISSN
1078-0998
E-ISSN
1536-4844
DOI
10.1093/ibd/izae020.117
