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NRF2 activators restrict coronaviruses by targeting a network involving ACE2, TMPRSS2, and XPO1

NRF2 activators restrict coronaviruses by targeting a network involving ACE2, TMPRSS2, and XPO1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3170647096

NRF2 activators restrict coronaviruses by targeting a network involving ACE2, TMPRSS2, and XPO1

About this item

Full title

NRF2 activators restrict coronaviruses by targeting a network involving ACE2, TMPRSS2, and XPO1

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2025-02

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Nuclear factor erythroid 2-related factor 2 (NRF2) is a master regulator of anti-oxidative and detoxifying cell responses. In addition, it plays important roles in host cell defenses against pathogenic viruses, and small molecules that activate NRF2 signaling can exert potent antiviral effects. We recently found that the NRF2 activators 4-octyl ita...

Alternative Titles

Full title

NRF2 activators restrict coronaviruses by targeting a network involving ACE2, TMPRSS2, and XPO1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_3170647096

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3170647096

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2025.02.24.639813