NRF2 activators restrict coronaviruses by targeting a network involving ACE2, TMPRSS2, and XPO1
NRF2 activators restrict coronaviruses by targeting a network involving ACE2, TMPRSS2, and XPO1
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Nuclear factor erythroid 2-related factor 2 (NRF2) is a master regulator of anti-oxidative and detoxifying cell responses. In addition, it plays important roles in host cell defenses against pathogenic viruses, and small molecules that activate NRF2 signaling can exert potent antiviral effects. We recently found that the NRF2 activators 4-octyl ita...
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NRF2 activators restrict coronaviruses by targeting a network involving ACE2, TMPRSS2, and XPO1
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TN_cdi_proquest_journals_3170647096
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3170647096
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2692-8205
DOI
10.1101/2025.02.24.639813
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https://www.proquest.com/docview/3170647096?pq-origsite=primo&accountid=13902