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EPAS1 Gain-of-Function Mutation Contributes to High-Altitude Adaptation in Tibetan Horses

EPAS1 Gain-of-Function Mutation Contributes to High-Altitude Adaptation in Tibetan Horses

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3170905512

EPAS1 Gain-of-Function Mutation Contributes to High-Altitude Adaptation in Tibetan Horses

About this item

Full title

EPAS1 Gain-of-Function Mutation Contributes to High-Altitude Adaptation in Tibetan Horses

Publisher

United States: Oxford University Press

Journal title

Molecular biology and evolution, 2019-11, Vol.36 (11), p.2591-2603

Language

English

Formats

Publication information

Publisher

United States: Oxford University Press

More information

Scope and Contents

Contents

High altitude represents some of the most extreme environments worldwide. The genetic changes underlying adaptation to such environments have been recently identified in multiple animals but remain unknown in horses. Here, we sequence the complete genome of 138 domestic horses encompassing a whole altitudinal range across China to uncover the genet...

Alternative Titles

Full title

EPAS1 Gain-of-Function Mutation Contributes to High-Altitude Adaptation in Tibetan Horses

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_3170905512

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3170905512

Other Identifiers

ISSN

0737-4038

E-ISSN

1537-1719

DOI

10.1093/molbev/msz158

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