Substrate Ambiguous Enzymes within the Escherichia coli Proteome Offer Different Evolutionary Soluti...
Substrate Ambiguous Enzymes within the Escherichia coli Proteome Offer Different Evolutionary Solutions to the Same Problem
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United States: Oxford University Press
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English
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United States: Oxford University Press
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Many enzymes exhibit some catalytic promiscuity or substrate ambiguity. These weak activities do not affect the fitness of the organism under ordinary circumstances, but can serve as potential evolutionary precursors of new catalytic functions. We wondered whether different proteins with the same substrate ambiguous activity evolve differently unde...
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Substrate Ambiguous Enzymes within the Escherichia coli Proteome Offer Different Evolutionary Solutions to the Same Problem
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TN_cdi_proquest_journals_3171257110
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3171257110
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ISSN
0737-4038
E-ISSN
1537-1719
DOI
10.1093/molbev/mst105