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Substrate Ambiguous Enzymes within the Escherichia coli Proteome Offer Different Evolutionary Soluti...

Substrate Ambiguous Enzymes within the Escherichia coli Proteome Offer Different Evolutionary Soluti...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3171257110

Substrate Ambiguous Enzymes within the Escherichia coli Proteome Offer Different Evolutionary Solutions to the Same Problem

About this item

Full title

Substrate Ambiguous Enzymes within the Escherichia coli Proteome Offer Different Evolutionary Solutions to the Same Problem

Publisher

United States: Oxford University Press

Journal title

Molecular biology and evolution, 2013-09, Vol.30 (9), p.2001-2012

Language

English

Formats

Publication information

Publisher

United States: Oxford University Press

More information

Scope and Contents

Contents

Many enzymes exhibit some catalytic promiscuity or substrate ambiguity. These weak activities do not affect the fitness of the organism under ordinary circumstances, but can serve as potential evolutionary precursors of new catalytic functions. We wondered whether different proteins with the same substrate ambiguous activity evolve differently unde...

Alternative Titles

Full title

Substrate Ambiguous Enzymes within the Escherichia coli Proteome Offer Different Evolutionary Solutions to the Same Problem

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_3171257110

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3171257110

Other Identifiers

ISSN

0737-4038

E-ISSN

1537-1719

DOI

10.1093/molbev/mst105

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