Ancient Whole Genome Enrichment Using Baits Built from Modern DNA
Ancient Whole Genome Enrichment Using Baits Built from Modern DNA
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Publisher
United States: Oxford University Press
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Language
English
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Publisher
United States: Oxford University Press
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We report metrics from complete genome capture of nuclear DNA from extinct mammoths using biotinylated RNAs transcribed from an Asian elephant DNA extract. Enrichment of the nuclear genome ranged from 1.06- to 18.65-fold, to an apparent maximum threshold of ∼80% on-target. This projects an order of magnitude less costly complete genome sequencing f...
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Full title
Ancient Whole Genome Enrichment Using Baits Built from Modern DNA
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TN_cdi_proquest_journals_3171257346
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3171257346
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ISSN
0737-4038
E-ISSN
1537-1719
DOI
10.1093/molbev/msu074
