DNA Editing of LTR Retrotransposons Reveals the Impact of APOBECs on Vertebrate Genomes
DNA Editing of LTR Retrotransposons Reveals the Impact of APOBECs on Vertebrate Genomes
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United States: Oxford University Press
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English
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United States: Oxford University Press
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Long terminal repeat retrotransposons (LTR) are widespread in vertebrates and their dynamism facilitates genome evolution. However, these endogenous retroviruses (ERVs) must be restricted to maintain genomic stability. The APOBECs, a protein family that can edit C-to-U in DNA, do so by interfering with reverse transcription and hypermutating retrot...
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DNA Editing of LTR Retrotransposons Reveals the Impact of APOBECs on Vertebrate Genomes
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TN_cdi_proquest_journals_3171292163
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3171292163
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ISSN
0737-4038
E-ISSN
1537-1719
DOI
10.1093/molbev/msv239
