Identification of Lineage-Specific Cis-Regulatory Modules Associated with Variation in Transcription...
Identification of Lineage-Specific Cis-Regulatory Modules Associated with Variation in Transcription Factor Binding and Chromatin Activity Using Ornstein–Uhlenbeck Models
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United States: Oxford University Press
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English
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United States: Oxford University Press
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Scoring the impact of noncoding variation on the function of cis-regulatory regions, on their chromatin state, and on the qualitative and quantitative expression levels of target genes is a fundamental problem in evolutionary genomics. A particular challenge is how to model the divergence of quantitative traits and to identify relationships between...
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Full title
Identification of Lineage-Specific Cis-Regulatory Modules Associated with Variation in Transcription Factor Binding and Chromatin Activity Using Ornstein–Uhlenbeck Models
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TN_cdi_proquest_journals_3171294533
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3171294533
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ISSN
0737-4038
E-ISSN
1537-1719
DOI
10.1093/molbev/msv107
