An actin-regulated importin [alpha]/[beta]-dependent extended bipartite NLS directs nuclear import o...
An actin-regulated importin [alpha]/[beta]-dependent extended bipartite NLS directs nuclear import of MRTF-A
About this item
Full title
Author / Creator
Publisher
New York: Springer Nature B.V
Journal title
Language
English
Formats
Publication information
Publisher
New York: Springer Nature B.V
Subjects
More information
Scope and Contents
Contents
Myocardin-related transcription factors (MRTFs) are actin-regulated transcriptional coactivators, which bind G-actin through their N-terminal RPEL domains. In response to signal-induced actin polymerisation and concomitant G-actin depletion, MRTFs accumulate in the nucleus and activate target gene transcription through their partner protein SRF. Nu...
Alternative Titles
Full title
An actin-regulated importin [alpha]/[beta]-dependent extended bipartite NLS directs nuclear import of MRTF-A
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_759534804
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_759534804
Other Identifiers
ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/emboj.2010.216
