Specific erythroid-lineage defect in mice conditionally deficient for Mediator subunit Med1
Specific erythroid-lineage defect in mice conditionally deficient for Mediator subunit Med1
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The Mediator complex forms the bridge between transcriptional activators and the RNA polymerase II. Med1 (also known as PBP or TRAP220) is a key component of Mediator that interacts with nuclear hormone receptors and GATA transcription factors. Here, we show dynamic recruitment of GATA-1, TFIIB, Mediator, and RNA polymerase II to the β-globin locus...
Alternative Titles
Full title
Specific erythroid-lineage defect in mice conditionally deficient for Mediator subunit Med1
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TN_cdi_proquest_journals_818549130
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_818549130
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1005794107
