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Lipid packing drives the segregation of transmembrane helices into disordered lipid domains in model...

Lipid packing drives the segregation of transmembrane helices into disordered lipid domains in model...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_848011620

Lipid packing drives the segregation of transmembrane helices into disordered lipid domains in model membranes

About this item

Full title

Lipid packing drives the segregation of transmembrane helices into disordered lipid domains in model membranes

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2011-01, Vol.108 (4), p.1343-1348

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Cell membranes are comprised of multicomponent lipid and protein mixtures that exhibit a complex partitioning behavior. Regions of structural and compositional heterogeneity play a major role in the sorting and self-assembly of proteins, and their clustering into higher-order oligomers. Here, we use computer simulations and optical microscopy to st...

Alternative Titles

Full title

Lipid packing drives the segregation of transmembrane helices into disordered lipid domains in model membranes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_848011620

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_848011620

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1009362108

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