Glucocorticoid enhances hypoxia- and/or transforming growth factor-[beta]-induced plasminogen activa...
Glucocorticoid enhances hypoxia- and/or transforming growth factor-[beta]-induced plasminogen activator inhibitor-1 production in human proximal renal tubular cells
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Publisher
Tokyo: Springer Nature B.V
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Language
English
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Publisher
Tokyo: Springer Nature B.V
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Scope and Contents
Contents
Glucocorticoid (GC) treatment reportedly exaggerates renal fibrosis in progressive kidney diseases during which hypoxia occurs as an unavoidable consequence in renal tubular cells. Two major fibrotic factors, hypoxia and transforming growth factor-β (TGF-β), upregulate the production of plasminogen activator inhibitor-1 (PAI-1), a fibrosis enhancer...
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Full title
Glucocorticoid enhances hypoxia- and/or transforming growth factor-[beta]-induced plasminogen activator inhibitor-1 production in human proximal renal tubular cells
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TN_cdi_proquest_journals_851944636
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_851944636
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ISSN
1342-1751
E-ISSN
1437-7799
DOI
10.1007/s10157-010-0351-7
