PET of (R)-^sup 11^C-Rolipram Binding to Phosphodiesterase-4 Is Reproducible and Sensitive to Increa...
PET of (R)-^sup 11^C-Rolipram Binding to Phosphodiesterase-4 Is Reproducible and Sensitive to Increased Norepinephrine in the Rat Heart
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New York: Society of Nuclear Medicine
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Language
English
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New York: Society of Nuclear Medicine
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Phosphodiesterase-4 (PDE4) plays a critical role in the regulation of β-adrenergic receptor-stimulated cyclic adenosine monophosphate cell signaling in the heart. (R)-rolipram, a PDE4-selective inhibitor, has been studied previously as a radiotracer for the quantification of PDE4 levels. The aim of this study was to characterize (R)-^sup 11^C-rolip...
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Full title
PET of (R)-^sup 11^C-Rolipram Binding to Phosphodiesterase-4 Is Reproducible and Sensitive to Increased Norepinephrine in the Rat Heart
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TN_cdi_proquest_journals_853890143
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_853890143
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ISSN
0161-5505
E-ISSN
1535-5667
