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Molecular basis of purine-rich RNA recognition by the human SR-like protein Tra2-[beta]1

Molecular basis of purine-rich RNA recognition by the human SR-like protein Tra2-[beta]1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_860919173

Molecular basis of purine-rich RNA recognition by the human SR-like protein Tra2-[beta]1

About this item

Full title

Molecular basis of purine-rich RNA recognition by the human SR-like protein Tra2-[beta]1

Publisher

New York: Nature Publishing Group

Journal title

Nature structural & molecular biology, 2011-04, Vol.18 (4), p.443

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group

More information

Scope and Contents

Contents

Tra2-β1 is a unique splicing factor as its single RNA recognition motif (RRM) is located between two RS (arginine-serine) domains. To understand how this protein recognizes its RNA target, we solved the structure of Tra2-β1 RRM in complex with RNA. The central 5[variant prime]-AGAA-3[variant prime] motif is specifically recognized by residues from...

Alternative Titles

Full title

Molecular basis of purine-rich RNA recognition by the human SR-like protein Tra2-[beta]1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_860919173

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_860919173

Other Identifiers

ISSN

1545-9993

E-ISSN

1545-9985

DOI

10.1038/nsmb.2001

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