A direct role for Met endocytosis in tumorigenesis
A direct role for Met endocytosis in tumorigenesis
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Compartmentalization of signals generated by receptor tyrosine kinase (RTK) endocytosis has emerged as a major determinant of various cell functions. Here, using tumour-associated Met-activating mutations, we demonstrate a direct link between endocytosis and tumorigenicity. Met mutants exhibit increased endocytosis/recycling activity and decreased...
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Full title
A direct role for Met endocytosis in tumorigenesis
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TN_cdi_proquest_journals_900176811
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_900176811
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb2257
