Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after fail...
Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/3 randomised trial
About this item
Full title
Author / Creator
Miller, Vincent A, Prof , Hirsh, Vera, MD , Cadranel, Jacques, Prof , Chen, Yuh-Min, MD , Park, Keunchil, Prof , Kim, Sang-We, Prof , Zhou, Caicun, Prof , Su, Wu-Chou, Prof , Wang, Mengzhao, Prof , Sun, Yan, Prof , Heo, Dae Seog, Prof , Crino, Lucio, Prof , Tan, Eng-Huat, MD , Chao, Tsu-Yi, Prof , Shahidi, Mehdi, MD , Cong, Xiuyu Julie, PhD , Lorence, Robert M, MD and Yang, James Chih-Hsin, Prof
Publisher
England: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
Summary Background Afatinib, an irreversible ErbB-family blocker, has shown preclinical activity when tested in EGFR mutant models with mutations that confer resistance to EGFR tyrosine-kinase inhibitors. We aimed to assess its efficacy in patients with advanced lung adenocarcinoma with previous treatment failure on EGFR tyrosine-kinase inhibitors....
Alternative Titles
Full title
Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/3 randomised trial
Authors, Artists and Contributors
Author / Creator
Hirsh, Vera, MD
Cadranel, Jacques, Prof
Chen, Yuh-Min, MD
Park, Keunchil, Prof
Kim, Sang-We, Prof
Zhou, Caicun, Prof
Su, Wu-Chou, Prof
Wang, Mengzhao, Prof
Sun, Yan, Prof
Heo, Dae Seog, Prof
Crino, Lucio, Prof
Tan, Eng-Huat, MD
Chao, Tsu-Yi, Prof
Shahidi, Mehdi, MD
Cong, Xiuyu Julie, PhD
Lorence, Robert M, MD
Yang, James Chih-Hsin, Prof
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1011199437
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1011199437
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(12)70087-6
