Microtubule and cortical forces determine platelet size during vascular platelet production
Microtubule and cortical forces determine platelet size during vascular platelet production
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Megakaryocytes release large preplatelet intermediates into the sinusoidal blood vessels. Preplatelets convert into barbell-shaped proplatelets
in vitro
to undergo repeated abscissions that yield circulating platelets. These observations predict the presence of circular-preplatelets and barbell-proplatelets in blood, and two fundamental quest...
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Full title
Microtubule and cortical forces determine platelet size during vascular platelet production
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TN_cdi_proquest_miscellaneous_1015756428
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1015756428
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms1838