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The PPARγ agonist rosiglitazone prevents cognitive impairment by inhibiting astrocyte activation and...

The PPARγ agonist rosiglitazone prevents cognitive impairment by inhibiting astrocyte activation and...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1017982455

The PPARγ agonist rosiglitazone prevents cognitive impairment by inhibiting astrocyte activation and oxidative stress following pilocarpine-induced status epilepticus

About this item

Full title

The PPARγ agonist rosiglitazone prevents cognitive impairment by inhibiting astrocyte activation and oxidative stress following pilocarpine-induced status epilepticus

Publisher

Milan: Springer Milan

Journal title

Neurological sciences, 2012-06, Vol.33 (3), p.559-566

Language

English

Formats

Publication information

Publisher

Milan: Springer Milan

More information

Scope and Contents

Contents

Epilepsy is commonly associated with cognitive impairment. Astrocyte activation and oxidative stress occur following seizures, and play a role in the pathological injury of epilepsy with cognitive impairment. The peroxisome proliferator-activated receptor gamma (PPARγ) has been shown to exhibit neuroprotective and antioxidative effects in CNS disea...

Alternative Titles

Full title

The PPARγ agonist rosiglitazone prevents cognitive impairment by inhibiting astrocyte activation and oxidative stress following pilocarpine-induced status epilepticus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1017982455

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1017982455

Other Identifiers

ISSN

1590-1874

E-ISSN

1590-3478

DOI

10.1007/s10072-011-0774-2

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