Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassort...
Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets
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Author / Creator
Imai, Masaki , Watanabe, Tokiko , Hatta, Masato , Das, Subash C. , Ozawa, Makoto , Shinya, Kyoko , Zhong, Gongxun , Hanson, Anthony , Katsura, Hiroaki , Watanabe, Shinji , Li, Chengjun , Kawakami, Eiryo , Yamada, Shinya , Kiso, Maki , Suzuki, Yasuo , Maher, Eileen A. , Neumann, Gabriele and Kawaoka, Yoshihiro
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Only four mutations in H5N1 HA are required to enable ferret-to-ferret transmission of a reassortant virus containing the H5 HA and the remaining seven gene segments from a human pandemic H1N1 influenza virus.
Elements involved in H5N1 transmission
Whether avian H5N1 viruses can gain the ability to transmit between humans was uncertain. The v...
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Full title
Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets
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Record Identifier
TN_cdi_proquest_miscellaneous_1021981928
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1021981928
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature10831