Early Response of Bone Marrow Osteoprogenitors to Skeletal Unloading and Sclerostin Antibody
Early Response of Bone Marrow Osteoprogenitors to Skeletal Unloading and Sclerostin Antibody
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Publisher
New York: Springer-Verlag
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Language
English
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Publisher
New York: Springer-Verlag
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Contents
Sclerostin functions as an antagonist to Wnt signaling and inhibits bone-forming activity. We studied the effects of skeletal unloading and treatment with sclerostin antibody (Scl-Ab) on mesenchymal stem cell, osteoprogenitor and osteoclast precursor pools, and their relationship to bone formation and resorption. Male C57BL/6 mice (5-months-old) we...
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Full title
Early Response of Bone Marrow Osteoprogenitors to Skeletal Unloading and Sclerostin Antibody
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TN_cdi_proquest_miscellaneous_1024668965
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1024668965
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ISSN
0171-967X
E-ISSN
1432-0827
DOI
10.1007/s00223-012-9610-9
