RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer ce...
RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer cell survival
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Author / Creator
Goidts, V , Bageritz, J , Puccio, L , Nakata, S , Zapatka, M , Barbus, S , Toedt, G , Campos, B , Korshunov, A , Momma, S , Van Schaftingen, E , Reifenberger, G , Herold-Mende, C , Lichter, P and Radlwimmer, B
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The concept of cancer stem-like cells (CSCs) has gained considerable attention in various solid tumors including glioblastoma, the most common primary brain tumor. This sub-population of tumor cells has been intensively investigated and their role in therapy resistance as well as tumor recurrence has been demonstrated. In that respect, development...
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RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer cell survival
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TN_cdi_proquest_miscellaneous_1028028615
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1028028615
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2011.490