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RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer ce...

RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer ce...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1028028615

RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer cell survival

About this item

Full title

RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer cell survival

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2012-07, Vol.31 (27), p.3235-3243

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The concept of cancer stem-like cells (CSCs) has gained considerable attention in various solid tumors including glioblastoma, the most common primary brain tumor. This sub-population of tumor cells has been intensively investigated and their role in therapy resistance as well as tumor recurrence has been demonstrated. In that respect, development...

Alternative Titles

Full title

RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer cell survival

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1028028615

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1028028615

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/onc.2011.490

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