Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma
Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma
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Author / Creator
Shakhova, Olga , Zingg, Daniel , Schaefer, Simon M. , Hari, Lisette , Civenni, Gianluca , Blunschi, Jacqueline , Claudinot, Stéphanie , Okoniewski, Michal , Beermann, Friedrich , Mihic-Probst, Daniela , Moch, Holger , Wegner, Michael , Dummer, Reinhard , Barrandon, Yann , Cinelli, Paolo and Sommer, Lukas
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Shakhova, Sommer and colleagues use mouse models to demonstrate that the Sox10 transcription factor is crucial for the formation and maintenance of giant congenital naevi and melanoma. They show, in human melanoma cells, that Sox10 promotes neural crest stem cell properties, cell proliferation and cell survival.
Giant congenital naevi are pigmen...
Alternative Titles
Full title
Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma
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Record Identifier
TN_cdi_proquest_miscellaneous_1031162324
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1031162324
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb2535
