The NAD metabolome — a key determinant of cancer cell biology
The NAD metabolome — a key determinant of cancer cell biology
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
NAD is an important redox factor and substrate in various signalling processes, in which it is irreversibly degraded to form molecules that are of key relevance to cellular homeostasis. Both NAD
+
-dependent metabolic and signalling pathways are altered in cancer cells, providing a number of potential drug targets.
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Full title
The NAD metabolome — a key determinant of cancer cell biology
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TN_cdi_proquest_miscellaneous_1171875654
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1171875654
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ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/nrc3340
