Absence of signaling into CD4+ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and in...
Absence of signaling into CD4+ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3+ regulatory T cells
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Complement provides costimulatory signals to T cells. Medof and colleagues demonstrate that an absence of complement signaling in naive T cells generates an autoinductive loop to drive induced regulatory T cells.
Signaling through the G protein–coupled receptors for the complement fragments C3a and C5a (C3aR and C5aR, respectively) by dendritic...
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Absence of signaling into CD4+ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3+ regulatory T cells
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TN_cdi_proquest_miscellaneous_1273697853
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1273697853
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1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.2499
