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Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4+ T cell immu...

Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4+ T cell immu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1288995561

Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4+ T cell immunity

About this item

Full title

Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4+ T cell immunity

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2013-03, Vol.14 (3), p.271-280

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

CD4
+
and CD8
+
T cells are considered distinct functional lymphocyte subsets. Cheroutre and Mucida and their colleagues show that mature gut-associated CD4
+
T cells lose ThPOK expression and reactivate CD8 cytolytic effector programs.
The gut mucosa hosts large numbers of activated lymphocytes that are exposed to stimuli from...

Alternative Titles

Full title

Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4+ T cell immunity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1288995561

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1288995561

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni.2518

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