Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4+ T cell immu...
Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4+ T cell immunity
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
CD4
+
and CD8
+
T cells are considered distinct functional lymphocyte subsets. Cheroutre and Mucida and their colleagues show that mature gut-associated CD4
+
T cells lose ThPOK expression and reactivate CD8 cytolytic effector programs.
The gut mucosa hosts large numbers of activated lymphocytes that are exposed to stimuli from...
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Full title
Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4+ T cell immunity
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TN_cdi_proquest_miscellaneous_1288995561
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1288995561
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.2518