Contribution of Tight Junction Proteins to Ion, Macromolecule, and Water Barrier in Keratinocytes
Contribution of Tight Junction Proteins to Ion, Macromolecule, and Water Barrier in Keratinocytes
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United States: Elsevier Inc
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Language
English
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United States: Elsevier Inc
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Contents
Tight junctions (TJs) form a selective barrier for ions, water, and macromolecules in simple epithelia. In keratinocytes and epidermis, TJs were shown to be involved in individual barrier functions. The absence of the TJ protein claudin-1 (Cldn1) in mice results in a skin-barrier defect characterized by lethal water loss. However, detailed molecula...
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Full title
Contribution of Tight Junction Proteins to Ion, Macromolecule, and Water Barrier in Keratinocytes
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TN_cdi_proquest_miscellaneous_1331086349
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1331086349
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ISSN
0022-202X
E-ISSN
1523-1747
DOI
10.1038/jid.2012.507
