GLP-1 receptor activation and Epac2 link atrial natriuretic peptide secretion to control of blood pr...
GLP-1 receptor activation and Epac2 link atrial natriuretic peptide secretion to control of blood pressure
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
The peptide hormone GLP-1 has both antidiabetic and antihypertensive effects. Daniel Drucker and his colleagues now show that GLP-1 lowers blood pressure through indirect mechanisms involving the heart: GLP-1 acts on its receptor in atrial cardiomyocytes to stimulate secretion of the peptide hormone ANP, which in turn lowers blood pressure through...
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Full title
GLP-1 receptor activation and Epac2 link atrial natriuretic peptide secretion to control of blood pressure
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TN_cdi_proquest_miscellaneous_1349704959
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1349704959
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.3128
