Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota
Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
By using high-throughput sequencing of T-cell receptors, this study shows that thymus-derived regulatory T (T
reg
) cells constitute most T
reg
cells in all lymphoid and intestinal organs, including the colon, suggesting that thymic T
reg
cells and not induced T
reg
cells dominantly control tolerance to the gut’s antigens su...
Alternative Titles
Full title
Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota
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Record Identifier
TN_cdi_proquest_miscellaneous_1350151211
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1350151211
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature12079
