Association of enhanced activity of indoleamine 2,3-dioxygenase in dendritic cells with the inductio...
Association of enhanced activity of indoleamine 2,3-dioxygenase in dendritic cells with the induction of regulatory T cells in chronic hepatitis C infection
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Author / Creator
Higashitani, Koyo , Kanto, Tatsuya , Kuroda, Shoko , Yoshio, Sachiyo , Matsubara, Tokuhiro , Kakita, Naruyasu , Oze, Tsugiko , Miyazaki, Masanori , Sakakibara, Mitsuru , Hiramatsu, Naoki , Mita, Eiji , Imai, Yasuharu , Kasahara, Akinori , Okuno, Alato , Takikawa, Osamu , Hayashi, Norio and Takehara, Tetsuo
Publisher
Japan: Springer Japan
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Language
English
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Publisher
Japan: Springer Japan
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Background
Altered functions of dendritic cells (DCs) and/or increases of regulatory T cells (Tregs) are involved in the pathogenesis of chronic hepatitis C virus (HCV) infection. A tryptophan-catabolizing enzyme, indoleamine 2,3-dioxygenase (IDO), is reported to be an inducer of immune tolerance. Our aim was to clarify whether or not IDO is act...
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Full title
Association of enhanced activity of indoleamine 2,3-dioxygenase in dendritic cells with the induction of regulatory T cells in chronic hepatitis C infection
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Record Identifier
TN_cdi_proquest_miscellaneous_1367487886
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1367487886
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ISSN
0944-1174
E-ISSN
1435-5922
DOI
10.1007/s00535-012-0667-z