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Clinical factors associated with the therapeutic efficacy of atezolizumab plus bevacizumab in patients with unresectable hepatocellular carcinoma: A multicenter prospective observational study
Author / Creator:Kai, Machiko ; Hikita, Hayato ; Kazuki, Maesaka ; Tahata, Yuki ; Shinkai, Kazuma ; Doi, Akira ; Ohkawa, Kazuyoshi ; Miyazaki, Masanori ; Ishida, Hisashi ; Matsumoto, Kengo ; Nozaki, Yasutoshi ; Yakushijin, Takayuki ; Sakamori, Ryotaro ; Kaneko, Akira ; Iio, Sadaharu ; Nawa, Takatoshi ; Kakita, Naruyasu ; Morishita, Naoki ; Hiramatsu, Naoki ; Usui, Takeo ; Imanaka, Kazuho ; Doi, Yoshinori ; Sakakibara, Mitsuru ; Yoshida, Yuichi ; Oze, Tsugiko ; Kodama, Takahiro ; Tatsumi, Tomohide ; Takehara, Tetsuo
Publisher:United States: Public Library of Science
Journal title:PloS one, 2024-01, Vol.19 (1), p.e0294590-e0294590
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A randomized, double-blind study to evaluate the acid-inhibitory effect of vonoprazan (20 mg and 40 mg) in patients with proton-pump inhibitor-resistant erosive esophagitis
Author / Creator:Iwakiri, Katsuhiko ; Sakurai, Yuuichi ; Shiino, Madoka ; Okamoto, Hiroyuki ; Kudou, Kentaro ; Nishimura, Akira ; Hiramatsu, Naoki ; Umegaki, Eiji ; Ashida, Kiyoshi
Publisher:London, England: SAGE Publications
Journal title:Therapeutic advances in gastroenterology, 2017-06, Vol.10 (6), p.439-451
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Pretreatment with antibiotics is associated with reduced therapeutic response to atezolizumab plus bevacizumab in patients with hepatocellular carcinoma
Author / Creator:Maesaka, Kazuki ; Sakamori, Ryotaro ; Yamada, Ryoko ; Doi, Akira ; Tahata, Yuki ; Ohkawa, Kazuyoshi ; Oshita, Masahide ; Miyazaki, Masanori ; Yakushijin, Takayuki ; Nozaki, Yasutoshi ; Matsumoto, Kengo ; Tanaka, Satoshi ; Kaneko, Akira ; Iio, Sadaharu ; Nawa, Takatoshi ; Yamada, Yukinori ; Morishita, Naoki ; Usui, Takeo ; Hiramatsu, Naoki ; Doi, Yoshinori ; Sakakibara, Mitsuru ; Imanaka, Kazuho ; Yoshida, Yuichi ; Kodama, Takahiro ; Hikita, Hayato ; Tatsumi, Tomohide ; Takehara, Tetsuo
Publisher:United States: Public Library of Science
Journal title:PloS one, 2023-02, Vol.18 (2), p.e0281459-e0281459
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Prediction Model for Intrahepatic Distant Recurrence After Radiofrequency Ablation for Primary Hepatocellular Carcinoma 2 cm or Smaller
Author / Creator:Takigawa, Atsuo ; Sakamori, Ryotaro ; Tahata, Yuki ; Yoshioka, Teppei ; Yamada, Ryoko ; Kodama, Takahiro ; Hikita, Hayato ; Yakushijin, Takayuki ; Ohkawa, Kazuyoshi ; Hiramatsu, Naoki ; Mita, Eiji ; Hagiwara, Hideki ; Ito, Toshifmi ; Imai, Yasuharu ; Tatsumi, Tomohide ; Takehara, Tetsuo
Publisher:New York: Springer US
Journal title:Digestive diseases and sciences, 2022-12, Vol.67 (12), p.5704-5711
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Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice
Author / Creator:Kodama, Takahiro ; Takehara, Tetsuo ; Hikita, Hayato ; Shimizu, Satoshi ; Shigekawa, Minoru ; Tsunematsu, Hinako ; Li, Wei ; Miyagi, Takuya ; Hosui, Atsushi ; Tatsumi, Tomohide ; Ishida, Hisashi ; Kanto, Tatsuya ; Hiramatsu, Naoki ; Kubota, Satoshi ; Takigawa, Masaharu ; Tomimaru, Yoshito ; Tomokuni, Akira ; Nagano, Hiroaki ; Doki, Yuichiro ; Mori, Masaki ; Hayashi, Norio
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2011-08, Vol.121 (8), p.3343-3356
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JNJ-4178 (adafosbuvir, odalasvir, and simeprevir) in Japanese patients with chronic hepatitis C virus genotype 1 or 2 infection with or without compensated cirrhosis: the Phase IIa OMEGA-3 study
Author / Creator:Takehara, Tetsuo ; Chayama, Kazuaki ; Kurosaki, Masayuki ; Yatsuhashi, Hiroshi ; Tanaka, Yasuhito ; Hiramatsu, Naoki ; Sakamoto, Naoya ; Asahina, Yasuhiro ; Nozaki, Akito ; Nakano, Toshikazu ; Hagiwara, Yosuke ; Shimizu, Hiroko ; Yoshida, Hiroki ; Huang, Yuhan ; Biermer, Michael ; Vijgen, Leen ; Hayashi, Norio
Publisher:Singapore: Springer Singapore
Journal title:Journal of gastroenterology, 2020-06, Vol.55 (6), p.640-652
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Lower Serum Sodium Levels Are Associated with the Therapeutic Effect of Sorafenib on Hepatocellular Carcinoma
Author / Creator:Kegasawa, Tadashi ; Sakamori, Ryotaro ; Maesaka, Kazuki ; Yamada, Ryoko ; Tahata, Yuki ; Urabe, Ayako ; Kodama, Takahiro ; Hikita, Hayato ; Imanaka, Kazuho ; Ohkawa, Kazuyoshi ; Hiramatsu, Naoki ; Oshita, Masahide ; Yamada, Yukinori ; Inada, Masami ; Yakushijin, Takayuki ; Imai, Yasuharu ; Tatsumi, Tomohide ; Takehara, Tetsuo
Publisher:New York: Springer US
Journal title:Digestive diseases and sciences, 2021-05, Vol.66 (5), p.1720-1729
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Pilot study of tenofovir disoproxil fumarate and pegylated interferon-alpha 2a add-on therapy in Japanese patients with chronic hepatitis B
Author / Creator:Matsumoto, Akihiro ; Nishiguchi, Shuhei ; Enomoto, Hirayuki ; Tanaka, Yasuhito ; Shinkai, Noboru ; Okuse, Chiaki ; Kang, Jong-Hon ; Matsui, Takeshi ; Miyase, Shiho ; Yatsuhashi, Hiroshi ; Nagaoka, Shinya ; Kanda, Tatsuo ; Enomoto, Masaru ; Yamada, Ryoko ; Hiramatsu, Naoki ; Saito, Satoru ; Takaguchi, Koichi ; Ito, Kiyoaki ; Masaki, Tsutomu ; Morihara, Daisuke ; Tsuge, Masataka ; Chayama, Kazuaki ; Ikeda, Fusao ; Kagawa, Tatehiro ; Kondo, Yasuteru ; Murata, Kazumoto ; Tanaka, Eiji
Publisher:Singapore: Springer Singapore
Journal title:Journal of gastroenterology, 2020-10, Vol.55 (10), p.977-989
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Impact of alpha-fetoprotein on hepatocellular carcinoma development during entecavir treatment of chronic hepatitis B virus infection
Author / Creator:Yamada, Ryoko ; Hiramatsu, Naoki ; Oze, Tsugiko ; Morishita, Naoki ; Harada, Naoki ; Yakushijin, Takayuki ; Iio, Sadaharu ; Doi, Yoshinori ; Yamada, Akira ; Kaneko, Akira ; Hagiwara, Hideki ; Mita, Eiji ; Oshita, Masahide ; Itoh, Toshifumi ; Fukui, Hiroyuki ; Hijioka, Taizo ; Katayama, Kazuhiro ; Tamura, Shinji ; Yoshihara, Harumasa ; Imai, Yasuharu ; Kato, Michio ; Miyagi, Takuya ; Yoshida, Yuichi ; Tatsumi, Tomohide ; Kasahara, Akinori ; Hamasaki, Toshimitsu ; Hayashi, Norio ; Takehara, Tetsuo
Publisher:Tokyo: Springer Japan
Journal title:Journal of gastroenterology, 2015-07, Vol.50 (7), p.785-794
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Evaluation of Fucosylated Haptoglobin and Mac-2 Binding Protein as Serum Biomarkers to Estimate Liver Fibrosis in Patients with Chronic Hepatitis C
Author / Creator:Tawara, Seiichi ; Tatsumi, Tomohide ; Iio, Sadaharu ; Kobayashi, Ichizou ; Shigekawa, Minoru ; Hikita, Hayato ; Sakamori, Ryotaro ; Hiramatsu, Naoki ; Miyoshi, Eiji ; Takehara, Tetsuo
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-03, Vol.11 (3), p.e0151828-e0151828
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Serum Fucosylated Haptoglobin as a Novel Diagnostic Biomarker for Predicting Hepatocyte Ballooning and Nonalcoholic Steatohepatitis
Author / Creator:Kamada, Yoshihiro ; Akita, Maaya ; Takeda, Yuri ; Yamada, Shin ; Fujii, Hideki ; Sawai, Yoshiyuki ; Doi, Yoshinori ; Asazawa, Hitomi ; Nakayama, Kotarosumitomo ; Mizutani, Kayo ; Fujii, Hironobu ; Yakushijin, Takayuki ; Miyazaki, Masanori ; Ezaki, Hisao ; Hiramatsu, Naoki ; Yoshida, Yuichi ; Kiso, Shinichi ; Imai, Yasuharu ; Kawada, Norifumi ; Takehara, Tetsuo ; Miyoshi, Eiji
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-06, Vol.8 (6), p.e66328-e66328
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Involvement of GABAA receptors in 5-HT1A and σ1 receptor synergism on prefrontal dopaminergic transmission under circulating neurosteroid deficiency
Author / Creator:Ago, Yukio ; Hasebe, Shigeru ; Hiramatsu, Naoki ; Mori, Kazuya ; Watabe, Yuji ; Onaka, Yusuke ; Hashimoto, Hitoshi ; Takuma, Kazuhiro ; Matsuda, Toshio
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Psychopharmacology, 2016-09, Vol.233 (17), p.3125-3134
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Fluvoxamine enhances prefrontal dopaminergic neurotransmission in adrenalectomized/castrated mice via both 5-HT reuptake inhibition and σ1 receptor activation
Author / Creator:Ago, Yukio ; Yano, Koji ; Hiramatsu, Naoki ; Takuma, Kazuhiro ; Matsuda, Toshio
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:Psychopharmacologia, 2011-10, Vol.217 (3), p.377-386
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Association of enhanced activity of indoleamine 2,3-dioxygenase in dendritic cells with the induction of regulatory T cells in chronic hepatitis C infection
Author / Creator:Higashitani, Koyo ; Kanto, Tatsuya ; Kuroda, Shoko ; Yoshio, Sachiyo ; Matsubara, Tokuhiro ; Kakita, Naruyasu ; Oze, Tsugiko ; Miyazaki, Masanori ; Sakakibara, Mitsuru ; Hiramatsu, Naoki ; Mita, Eiji ; Imai, Yasuharu ; Kasahara, Akinori ; Okuno, Alato ; Takikawa, Osamu ; Hayashi, Norio ; Takehara, Tetsuo
Publisher:Japan: Springer Japan
Journal title:Journal of gastroenterology, 2013-05, Vol.48 (5), p.660-670
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Thrombospondin-2 as a Predictive Biomarker for Hepatocellular Carcinoma after Hepatitis C Virus Elimination by Direct-Acting Antiviral
Author / Creator:Matsumae, Takayuki ; Kodama, Takahiro ; Tahata, Yuki ; Myojin, Yuta ; Doi, Akira ; Nishio, Akira ; Yamada, Ryoko ; Nozaki, Yasutoshi ; Oshita, Masahide ; Hiramatsu, Naoki ; Morishita, Naoki ; Ohkawa, Kazuyoshi ; Hijioka, Taizo ; Sakakibara, Mitsuru ; Doi, Yoshinori ; Kakita, Naruyasu ; Yakushijin, Takayuki ; Sakamori, Ryotaro ; Hikita, Hayato ; Tatsumi, Tomohide ; Takehara, Tetsuo
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2023-01, Vol.15 (2), p.463
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STAT3 signaling within hepatocytes is required for anemia of inflammation in vivo
Author / Creator:Sakamori, Ryotaro ; Takehara, Tetsuo ; Tatsumi, Tomohide ; Shigekawa, Minoru ; Hikita, Hayato ; Hiramatsu, Naoki ; Kanto, Tatsuya ; Hayashi, Norio
Publisher:Japan: Japan : Springer Japan
Journal title:Journal of gastroenterology, 2010-02, Vol.45 (2), p.244-248
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Long-term effect of lamivudine treatment on the incidence of hepatocellular carcinoma in patients with hepatitis B virus infection
Author / Creator:Kurokawa, Mika ; Hiramatsu, Naoki ; Oze, Tsugiko ; Yakushijin, Takayuki ; Miyazaki, Masanori ; Hosui, Atsushi ; Miyagi, Takuya ; Yoshida, Yuichi ; Ishida, Hisashi ; Tatsumi, Tomohide ; Kiso, Shinichi ; Kanto, Tatsuya ; Kasahara, Akinori ; Iio, Sadaharu ; Doi, Yoshinori ; Yamada, Akira ; Oshita, Masahide ; Kaneko, Akira ; Mochizuki, Kiyoshi ; Hagiwara, Hideki ; Mita, Eiji ; Ito, Toshifumi ; Inui, Yoshiaki ; Katayama, Kazuhiro ; Yoshihara, Harumasa ; Imai, Yasuharu ; Hayashi, Eijirou ; Hayashi, Norio ; Takehara, Tetsuo
Publisher:Japan: Springer Japan
Journal title:Journal of gastroenterology, 2012-05, Vol.47 (5), p.577-585
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Baseline quasispecies selection and novel mutations contribute to emerging resistance-associated substitutions in hepatitis C virus after direct-acting antiviral treatment
Author / Creator:Kai, Yugo ; Hikita, Hayato ; Morishita, Naoki ; Murai, Kazuhiro ; Nakabori, Tasuku ; Iio, Sadaharu ; Hagiwara, Hideki ; Imai, Yasuharu ; Tamura, Shinji ; Tsutsui, Syusaku ; Naito, Masafumi ; Nishiuchi, Meiko ; Kondo, Yasuteru ; Kato, Takanobu ; Suemizu, Hiroshi ; Yamada, Ryoko ; Oze, Tsugiko ; Yakushijin, Takayuki ; Hiramatsu, Naoki ; Sakamori, Ryotaro ; Tatsumi, Tomohide ; Takehara, Tetsuo
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-01, Vol.7 (1), p.41660-41660, Article 41660
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Liver stiffness measurement by acoustic radiation force impulse is useful in predicting the presence of esophageal varices or high-risk esophageal varices among patients with HCV-related cirrhosis
Author / Creator:Morishita, Naoki ; Hiramatsu, Naoki ; Oze, Tsugiko ; Harada, Naoki ; Yamada, Ryoko ; Miyazaki, Masanori ; Yakushijin, Takayuki ; Miyagi, Takuya ; Yoshida, Yuichi ; Tatsumi, Tomohide ; Kanto, Tatsuya ; Takehara, Tetsuo
Publisher:Tokyo: Springer Japan
Journal title:Journal of gastroenterology, 2014-07, Vol.49 (7), p.1175-1182
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Combinational use of hepatitis B viral antigens predicts responses to nucleos(t)ide analogue/peg-interferon sequential therapy
Author / Creator:Matsumoto, Akihiro ; Nishiguchi, Shuhei ; Enomoto, Hirayuki ; Kang, Jong-Hon ; Tanaka, Yasuhito ; Shinkai, Noboru ; Kurosaki, Masayuki ; Enomoto, Masaru ; Kanda, Tatsuo ; Yokosuka, Osamu ; Yatsuhashi, Hiroshi ; Nagaoka, Shinya ; Okuse, Chiaki ; Kagawa, Tatehiro ; Mine, Tetsuya ; Takaguchi, Koichi ; Saito, Satoru ; Hino, Keisuke ; Ikeda, Fusao ; Sakisaka, Shotaro ; Morihara, Daisuke ; Miyase, Shiho ; Tsuge, Masataka ; Chayama, Kazuaki ; Hiramatsu, Naoki ; Suzuki, Yoshiyuki ; Murata, Kazumoto ; Tanaka, Eiji
Publisher:Tokyo: Springer Japan
Journal title:Journal of gastroenterology, 2018-02, Vol.53 (2), p.247-257
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Showing 1 to 20 of 92 results

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Clinical factors associated with the therapeutic efficacy of atezolizumab plus bevacizumab in patients with unresectable hepatocellular carcinoma: A multicenter prospective observational study

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A randomized, double-blind study to evaluate the acid-inhibitory effect of vonoprazan (20 mg and 40 mg) in patients with proton-pump inhibitor-resistant erosive esophagitis

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Pretreatment with antibiotics is associated with reduced therapeutic response to atezolizumab plus bevacizumab in patients with hepatocellular carcinoma

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Prediction Model for Intrahepatic Distant Recurrence After Radiofrequency Ablation for Primary Hepatocellular Carcinoma 2 cm or Smaller

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Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice

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JNJ-4178 (adafosbuvir, odalasvir, and simeprevir) in Japanese patients with chronic hepatitis C virus genotype 1 or 2 infection with or without compensated cirrhosis: the Phase IIa OMEGA-3 study

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Lower Serum Sodium Levels Are Associated with the Therapeutic Effect of Sorafenib on Hepatocellular Carcinoma

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Pilot study of tenofovir disoproxil fumarate and pegylated interferon-alpha 2a add-on therapy in Japanese patients with chronic hepatitis B

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Impact of alpha-fetoprotein on hepatocellular carcinoma development during entecavir treatment of chronic hepatitis B virus infection

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Evaluation of Fucosylated Haptoglobin and Mac-2 Binding Protein as Serum Biomarkers to Estimate Liver Fibrosis in Patients with Chronic Hepatitis C

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Serum Fucosylated Haptoglobin as a Novel Diagnostic Biomarker for Predicting Hepatocyte Ballooning and Nonalcoholic Steatohepatitis

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Involvement of GABAA receptors in 5-HT1A and σ1 receptor synergism on prefrontal dopaminergic transmission under circulating neurosteroid deficiency

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Fluvoxamine enhances prefrontal dopaminergic neurotransmission in adrenalectomized/castrated mice via both 5-HT reuptake inhibition and σ1 receptor activation

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Association of enhanced activity of indoleamine 2,3-dioxygenase in dendritic cells with the induction of regulatory T cells in chronic hepatitis C infection

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Thrombospondin-2 as a Predictive Biomarker for Hepatocellular Carcinoma after Hepatitis C Virus Elimination by Direct-Acting Antiviral

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STAT3 signaling within hepatocytes is required for anemia of inflammation in vivo

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Long-term effect of lamivudine treatment on the incidence of hepatocellular carcinoma in patients with hepatitis B virus infection

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Baseline quasispecies selection and novel mutations contribute to emerging resistance-associated substitutions in hepatitis C virus after direct-acting antiviral treatment

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Liver stiffness measurement by acoustic radiation force impulse is useful in predicting the presence of esophageal varices or high-risk esophageal varices among patients with HCV-related cirrhosis

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Combinational use of hepatitis B viral antigens predicts responses to nucleos(t)ide analogue/peg-interferon sequential therapy

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