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Glycyrrhizic acid (GCA) as 11β-hydroxysteroid dehydrogenase inhibitor exerts protective effect again...

Glycyrrhizic acid (GCA) as 11β-hydroxysteroid dehydrogenase inhibitor exerts protective effect again...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1367489987

Glycyrrhizic acid (GCA) as 11β-hydroxysteroid dehydrogenase inhibitor exerts protective effect against glucocorticoid-induced osteoporosis

About this item

Full title

Glycyrrhizic acid (GCA) as 11β-hydroxysteroid dehydrogenase inhibitor exerts protective effect against glucocorticoid-induced osteoporosis

Publisher

Japan: Springer Japan

Journal title

Journal of bone and mineral metabolism, 2013-05, Vol.31 (3), p.262-273

Language

English

Formats

Publication information

Publisher

Japan: Springer Japan

More information

Scope and Contents

Contents

Rapid onset of bone loss is a frequent complication of systemic glucocorticoid therapy which may lead to fragility fractures. Glucocorticoid action in bone depends upon the activity of 11β-hydroxysteroid dehydrogenase type 1 enzyme (11β-HSD1). Regulations of 11β-HSD1 activity may protect the bone against bone loss due to excess glucocorticoids. Gly...

Alternative Titles

Full title

Glycyrrhizic acid (GCA) as 11β-hydroxysteroid dehydrogenase inhibitor exerts protective effect against glucocorticoid-induced osteoporosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1367489987

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1367489987

Other Identifiers

ISSN

0914-8779

E-ISSN

1435-5604

DOI

10.1007/s00774-012-0413-x

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