α-Synuclein Vaccination Prevents the Accumulation of Parkinson Disease–Like Pathologic Inclusions in...
α-Synuclein Vaccination Prevents the Accumulation of Parkinson Disease–Like Pathologic Inclusions in Striatum in Association With Regulatory T Cell Recruitment in a Rat Model
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England: American Association of Neuropathologists, Inc
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Language
English
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Publisher
England: American Association of Neuropathologists, Inc
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ABSTRACTHuman leukocyte antigen-DR induction and lymphocyte infiltrates in the brains of patients with Parkinson disease (PD) and the presence in serum of α-synuclein (α-syn)–specific antibodies suggest that the peripheral immune system may have an active role in the progression of PD. We designed a vaccination strategy to attempt to control these...
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Full title
α-Synuclein Vaccination Prevents the Accumulation of Parkinson Disease–Like Pathologic Inclusions in Striatum in Association With Regulatory T Cell Recruitment in a Rat Model
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TN_cdi_proquest_miscellaneous_1372078322
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1372078322
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ISSN
0022-3069
E-ISSN
1554-6578
DOI
10.1097/NEN.0b013e31829768d2
