MiR-200b and miR-429 Function in Mouse Ovulation and Are Essential for Female Fertility
MiR-200b and miR-429 Function in Mouse Ovulation and Are Essential for Female Fertility
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United States: American Association for the Advancement of Science
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English
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United States: American Association for the Advancement of Science
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Ovulation in the mouse and other mammals is controlled by hormones secreted by the hypothalamo-pituitary-ovarian axis. We describe anovulation and infertility in female mice lacking the microRNAs miR-200b and miR-429. Both miRNAs are strongly expressed in the pituitary gland, where they suppress expression of the transcriptional repressor ZEB1. Eli...
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MiR-200b and miR-429 Function in Mouse Ovulation and Are Essential for Female Fertility
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TN_cdi_proquest_miscellaneous_1398435600
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1398435600
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1237999
