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Rapid construction of transgene-amplified CHO cell lines by cell cycle checkpoint engineering

Rapid construction of transgene-amplified CHO cell lines by cell cycle checkpoint engineering

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1399918654

Rapid construction of transgene-amplified CHO cell lines by cell cycle checkpoint engineering

About this item

Full title

Rapid construction of transgene-amplified CHO cell lines by cell cycle checkpoint engineering

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

Applied microbiology and biotechnology, 2013-07, Vol.97 (13), p.5731-5741

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

More information

Scope and Contents

Contents

The process of establishing high-producing cell lines for the manufacture of therapeutic proteins is usually both time-consuming and laborious due to the low probability of obtaining high-producing clones from a pool of transfected cells and slow cell growth under the strong selective pressure of screening to identify high-producing clones. We pres...

Alternative Titles

Full title

Rapid construction of transgene-amplified CHO cell lines by cell cycle checkpoint engineering

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1399918654

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1399918654

Other Identifiers

ISSN

0175-7598

E-ISSN

1432-0614

DOI

10.1007/s00253-013-4923-9

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