Rapid construction of transgene-amplified CHO cell lines by cell cycle checkpoint engineering
Rapid construction of transgene-amplified CHO cell lines by cell cycle checkpoint engineering
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Author / Creator
Publisher
Berlin/Heidelberg: Springer-Verlag
Journal title
Language
English
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Publisher
Berlin/Heidelberg: Springer-Verlag
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Scope and Contents
Contents
The process of establishing high-producing cell lines for the manufacture of therapeutic proteins is usually both time-consuming and laborious due to the low probability of obtaining high-producing clones from a pool of transfected cells and slow cell growth under the strong selective pressure of screening to identify high-producing clones. We pres...
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Full title
Rapid construction of transgene-amplified CHO cell lines by cell cycle checkpoint engineering
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Record Identifier
TN_cdi_proquest_miscellaneous_1399918654
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1399918654
Other Identifiers
ISSN
0175-7598
E-ISSN
1432-0614
DOI
10.1007/s00253-013-4923-9