Nicotinic α7 receptors enhance NMDA cognitive circuits in dorsolateral prefrontal cortex
Nicotinic α7 receptors enhance NMDA cognitive circuits in dorsolateral prefrontal cortex
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Washington, DC: National Academy of Sciences
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Language
English
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Washington, DC: National Academy of Sciences
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Contents
The cognitive function of the highly evolved dorsolateral prefrontal cortex (dlPFC) is greatly influenced by arousal state, and is gravely afflicted in disorders such as schizophrenia, where there are genetic insults in α7 nicotinic acetylcholine receptors (α7-nAChRs). A recent behavioral study indicates that ACh depletion from dlPFC markedly impai...
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Full title
Nicotinic α7 receptors enhance NMDA cognitive circuits in dorsolateral prefrontal cortex
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TN_cdi_proquest_miscellaneous_1401091267
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1401091267
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1307849110
