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SeeDB: a simple and morphology-preserving optical clearing agent for neuronal circuit reconstruction

SeeDB: a simple and morphology-preserving optical clearing agent for neuronal circuit reconstruction

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1419368060

SeeDB: a simple and morphology-preserving optical clearing agent for neuronal circuit reconstruction

About this item

Full title

SeeDB: a simple and morphology-preserving optical clearing agent for neuronal circuit reconstruction

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2013-08, Vol.16 (8), p.1154-1161

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

This technical report describes a method to clear fixed brain tissues while allowing for fluorescent dye tracing and retaining cellular morphology. The authors demonstrate the utility of the technique by obtaining a wiring diagram for sister mitral cells.
We report a water-based optical clearing agent, SeeDB, which clears fixed brain samples in...

Alternative Titles

Full title

SeeDB: a simple and morphology-preserving optical clearing agent for neuronal circuit reconstruction

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1419368060

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1419368060

Other Identifiers

ISSN

1097-6256

E-ISSN

1546-1726

DOI

10.1038/nn.3447

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