Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents...
Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance
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Author / Creator
Liew, Chong Wee , Boucher, Jeremie , Cheong, Jit Kong , Vernochet, Cecile , Koh, Ho-Jin , Mallol, Cristina , Townsend, Kristy , Langin, Dominique , Kawamori, Dan , Hu, Jiang , Tseng, Yu-Hua , Hellerstein, Marc K , Farmer, Stephen R , Goodyear, Laurie , Doria, Alessandro , Blüher, Matthias , Hsu, Stephen I-Hong and Kulkarni, Rohit N
Publisher
New York: Nature Publishing Group US
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English
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Publisher
New York: Nature Publishing Group US
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Contents
TRIP-Br2
–null mice are resistant to obesity and insulin resistance and have higher energy expenditure because of increased thermogenesis and oxidative metabolism. As expression of this transcriptional regulator is elevated in fat from obese humans, TRIP-Br2 might be a new therapeutic target against insulin resistance and hyperlipidemia.
Obes...
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Full title
Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance
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TN_cdi_proquest_miscellaneous_1427005971
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1427005971
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.3056
