Attenuation of Mouse Hepatitis Virus by Deletion of the LLRKxGxKG Region of Nsp1. e61166
Attenuation of Mouse Hepatitis Virus by Deletion of the LLRKxGxKG Region of Nsp1. e61166
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Author / Creator
Lei, Lin , Ying, Sun , Baojun, Luo , Yi, Yang , Xiang, He , Wenli, Su , Zounan, Sun , Deyin, Guo , Qingyu, Zhu and Jingmei, Liu
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Language
English
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Contents
Coronaviruses are a family of large positive-sense RNA viruses that are responsible for a wide range of important veterinary and human diseases. Nsp1 has been shown to have an important role in the pathogenetic mechanisms of coronaviruses in vivo. To assess the function of a relatively conserved domain (LLRKxGxKG) of MHV nsp1, a mutant virus, MHV-n...
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Full title
Attenuation of Mouse Hepatitis Virus by Deletion of the LLRKxGxKG Region of Nsp1. e61166
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TN_cdi_proquest_miscellaneous_1430858268
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1430858268
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E-ISSN
1932-6203
DOI
10.1371/journal.pone.0061166
