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The tumor suppressor Caliban regulates DNA damage-induced apoptosis through p53-dependent and -indep...

The tumor suppressor Caliban regulates DNA damage-induced apoptosis through p53-dependent and -indep...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1434018762

The tumor suppressor Caliban regulates DNA damage-induced apoptosis through p53-dependent and -independent activity

About this item

Full title

The tumor suppressor Caliban regulates DNA damage-induced apoptosis through p53-dependent and -independent activity

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2013-08, Vol.32 (33), p.3857-3866

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

We previously identified Caliban (Clbn) as the
Drosophila
homolog of human Serologically defined colon cancer antigen 1 gene and demonstrated that it could function as a tumor suppressor in human non-small-cell lung cancer (NSCLC) cells, although its mode of action was unknown. Herein, we identify roles for Clbn in DNA damage response. We gen...

Alternative Titles

Full title

The tumor suppressor Caliban regulates DNA damage-induced apoptosis through p53-dependent and -independent activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1434018762

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1434018762

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/onc.2012.395

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