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Preparation and incubation of precision-cut liver and intestinal slices for application in drug meta...

Preparation and incubation of precision-cut liver and intestinal slices for application in drug meta...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1434022744

Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies

About this item

Full title

Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies

Publisher

London: Nature Publishing Group UK

Journal title

Nature protocols, 2010-09, Vol.5 (9), p.1540-1551

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Precision-cut tissue slices (PCTS) are viable
ex vivo
explants of tissue with a reproducible, well defined thickness. They represent a mini-model of the organ under study and contain all cells of the tissue in their natural environment, leaving intercellular and cell-matrix interactions intact, and are therefore highly appropriate for studyin...

Alternative Titles

Full title

Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1434022744

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1434022744

Other Identifiers

ISSN

1754-2189

E-ISSN

1750-2799

DOI

10.1038/nprot.2010.111

How to access this item