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Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal...

Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1434024170

Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues

About this item

Full title

Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2012-11, Vol.44 (11), p.1207-1214

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Amos Tanay and colleagues characterize DNA methylation polymorphism within cell populations and track immortalized fibroblasts in culture for over 300 generations to show that formation of differentially methylated regions occurs through a stochastic process and nearly deterministic epigenetic remodeling.
DNA methylation has been comprehensively...

Alternative Titles

Full title

Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1434024170

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1434024170

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/ng.2442

How to access this item