Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal...
Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Amos Tanay and colleagues characterize DNA methylation polymorphism within cell populations and track immortalized fibroblasts in culture for over 300 generations to show that formation of differentially methylated regions occurs through a stochastic process and nearly deterministic epigenetic remodeling.
DNA methylation has been comprehensively...
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Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues
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TN_cdi_proquest_miscellaneous_1434024170
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1434024170
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ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.2442