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When mutants gain new powers: news from the mutant p53 field
Author / Creator:Brosh, Ran ; Rotter, Varda
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2009-10, Vol.9 (10), p.701-713
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Gain-of-Function Mutant p53: All the Roads Lead to Tumorigenesis
Author / Creator:Stein, Yan ; Rotter, Varda ; Aloni-Grinstein, Ronit
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2019-12, Vol.20 (24), p.6197
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p53 on the crossroad between regeneration and cancer
Author / Creator:Charni, Meital ; Aloni-Grinstein, Ronit ; Molchadsky, Alina ; Rotter, Varda
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2017-01, Vol.24 (1), p.8-14
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Visual barcodes for clonal-multiplexing of live microscopy-based assays
Author / Creator:Kaufman, Tom ; Nitzan, Erez ; Firestein, Nir ; Ginzberg, Miriam Bracha ; Iyengar, Seshu ; Patel, Nish ; Ben-Hamo, Rotem ; Porat, Ziv ; Hunter, Jaryd ; Hilfinger, Andreas ; Rotter, Varda ; Kafri, Ran ; Straussman, Ravid
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-05, Vol.13 (1), p.2725-2725, Article 2725
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Capturing tumor complexity in vitro: Comparative analysis of 2D and 3D tumor models for drug discovery
Author / Creator:Stock, Kristin ; Estrada, Marta F. ; Vidic, Suzana ; Gjerde, Kjersti ; Rudisch, Albin ; Santo, Vítor E. ; Barbier, Michaël ; Blom, Sami ; Arundkar, Sharath C. ; Selvam, Irwin ; Osswald, Annika ; Stein, Yan ; Gruenewald, Sylvia ; Brito, Catarina ; van Weerden, Wytske ; Rotter, Varda ; Boghaert, Erwin ; Oren, Moshe ; Sommergruber, Wolfgang ; Chong, Yolanda ; de Hoogt, Ronald ; Graeser, Ralph
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-07, Vol.6 (1), p.28951-28951, Article 28951
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ArticlesPeer ReviewedFull Text
Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues
Author / Creator:Landan, Gilad ; Cohen, Netta Mendelson ; Mukamel, Zohar ; Bar, Amir ; Molchadsky, Alina ; Brosh, Ran ; Horn-Saban, Shirley ; Zalcenstein, Daniela Amann ; Goldfinger, Naomi ; Zundelevich, Adi ; Gal-Yam, Einav Nili ; Rotter, Varda ; Tanay, Amos
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2012-11, Vol.44 (11), p.1207-1214
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Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers
Author / Creator:Solomon, Hilla ; Dinowitz, Nathan ; Pateras, Ioannis S. ; Cooks, Tomer ; Shetzer, Yoav ; Molchadsky, Alina ; Charni, Meital ; Rabani, Stav ; Koifman, Gabriela ; Tarcic, Ohad ; Porat, Ziv ; Kogan-Sakin, Ira ; Goldfinger, Naomi ; Oren, Moshe ; Harris, Curtis C. ; Gorgoulis, Vassilis G. ; Rotter, Varda
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2018-03, Vol.37 (12), p.1669-1684
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Diverse p53/DNA binding modes expand the repertoire of p53 response elements
Author / Creator:Vyas, Pratik ; Beno, Itai ; Xi, Zhiqun ; Stein, Yan ; Golovenko, Dmitrij ; Kessler, Naama ; Rotter, Varda ; Shakked, Zippora ; Haran, Tali E.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-10, Vol.114 (40), p.10624-10629
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ArticlesPeer ReviewedFull Text
High Throughput Analysis of Golgi Structure by Imaging Flow Cytometry
Author / Creator:Wortzel, Inbal ; Koifman, Gabriela ; Rotter, Varda ; Seger, Rony ; Porat, Ziv
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-04, Vol.7 (1), p.788-788, Article 788
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Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
Author / Creator:Lü, YiQing ; Cho, Tiffany ; Mukherjee, Saptaparna ; Suarez, Carmen Florencia ; Gonzalez-Foutel, Nicolas S ; Malik, Ahmad ; Martinez, Sebastien ; Dervovic, Dzana ; Oh, Robin Hyunseo ; Langille, Ellen ; Al-Zahrani, Khalid N ; Hoeg, Lisa ; Lin, Zhen Yuan ; Tsai, Ricky ; Mbamalu, Geraldine ; Rotter, Varda ; Ashton-Prolla, Patricia ; Moffat, Jason ; Chemes, Lucia Beatriz ; Gingras, Anne-Claude ; Oren, Moshe ; Durocher, Daniel ; Schramek, Daniel
Publisher:London: Nature Publishing Group UK
Journal title:Molecular systems biology, 2024-06, Vol.20 (6), p.719-740
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ArticlesPeer ReviewedFull Text
Pla2g16 phospholipase mediates gain-of-function activities of mutant p53
Author / Creator:Xiong, Shunbin ; Tu, Huolin ; Kollareddy, Madhusudhan ; Pant, Vinod ; Li, Qin ; Zhang, Yun ; Jackson, James G. ; Suh, Young-Ah ; Elizondo-Fraire, Ana C. ; Yang, Peirong ; Chau, Gilda ; Tashakori, Mehrnoosh ; Wasylishen, Amanda R. ; Ju, Zhenlin ; Solomon, Hilla ; Rotter, Varda ; Liu, Bin ; El-Naggar, Adel K. ; Donehower, Lawrence A. ; Martinez, Luis Alfonso ; Lozano, Guillermina
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (30), p.11145-11150
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ArticlesPeer ReviewedFull Text
TMPRSS2/ERG Promotes Epithelial to Mesenchymal Transition through the ZEB1/ZEB2 Axis in a Prostate Cancer Model
Author / Creator:Leshem, Orit ; Madar, Shalom ; Kogan-Sakin, Ira ; Kamer, Iris ; Goldstein, Ido ; Brosh, Ran ; Cohen, Yehudit ; Jacob-Hirsch, Jasmine ; Ehrlich, Marcelo ; Ben-Sasson, Shmuel ; Goldfinger, Naomi ; Loewenthal, Ron ; Gazit, Ephraim ; Rotter, Varda ; Berger, Raanan
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-07, Vol.6 (7), p.e21650-e21650
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ArticlesPeer ReviewedFull Text
p53 Plays a Role in Mesenchymal Differentiation Programs, in a Cell Fate Dependent Manner
Author / Creator:Molchadsky, Alina ; Shats, Igor ; Goldfinger, Naomi ; Pevsner-Fischer, Meirav ; Olson, Melissa ; Rinon, Ariel ; Tzahor, Eldad ; Lozano, Guillermina ; Zipori, Dov ; Sarig, Rachel ; Rotter, Varda
Publisher:United States: Public Library of Science
Journal title:PloS one, 2008-11, Vol.3 (11), p.e3707-e3707
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Global profiling of histone and DNA methylation reveals epigenetic-based regulation of gene expression during epithelial to mesenchymal transition in prostate cells
Author / Creator:Ke, Xi-Song ; Qu, Yi ; Cheng, Yang ; Li, Wen-Cheng ; Rotter, Varda ; Øyan, Anne Margrete ; Kalland, Karl-Henning
Publisher:England: BioMed Central Ltd
Journal title:BMC genomics, 2010-11, Vol.11 (1), p.669-669, Article 669
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ArticlesPeer ReviewedFull Text
Rescue of embryonic stem cells from cellular transformation by proteomic stabilization of mutant p53 and conversion into WT conformation
Author / Creator:Rivlin, Noa ; Katz, Shir ; Doody, Maayan ; Sheffer, Michal ; Horesh, Stav ; Molchadsky, Alina ; Koifman, Gabriela ; Shetzer, Yoav ; Goldfinger, Naomi ; Rotter, Varda ; Geiger, Tamar
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-05, Vol.111 (19), p.7006-7011
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TM7SF3, a novel p53-regulated homeostatic factor, attenuates cellular stress and the subsequent induction of the unfolded protein response
Author / Creator:Isaac, Roi ; Goldstein, Ido ; Furth, Noa ; Zilber, Neta ; Streim, Sarina ; Boura-Halfon, Sigalit ; Elhanany, Eytan ; Rotter, Varda ; Oren, Moshe ; Zick, Yehiel
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2017-01, Vol.24 (1), p.132-143
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Genome-Wide Profiling of Histone H3 Lysine 4 and Lysine 27 Trimethylation Reveals an Epigenetic Signature in Prostate Carcinogenesis
Author / Creator:Ke, Xi-Song ; Qu, Yi ; Rostad, Kari ; Li, Wen-Cheng ; Lin, Biaoyang ; Halvorsen, Ole Johan ; Haukaas, Svein A. ; Jonassen, Inge ; Petersen, Kjell ; Goldfinger, Naomi ; Rotter, Varda ; Akslen, Lars A. ; Oyan, Anne M. ; Kalland, Karl-Henning
Publisher:United States: Public Library of Science
Journal title:PloS one, 2009-03, Vol.4 (3), p.e4687
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ArticlesPeer ReviewedFull Text
On a fundamental structure of gene networks in living cells
Author / Creator:Kravchenko-Balasha, Nataly ; Levitzki, Alexander ; Goldstein, Andrew ; Rotter, Varda ; Gross, A. ; Remacle, F. ; Levine, R. D.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-03, Vol.109 (12), p.4702-4707
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ArticlesPeer ReviewedFull Text
Activated p53 suppresses the histone methyltransferase EZH2 gene
Author / Creator:Tang, Xiaohu ; Milyavsky, Michael ; Shats, Igor ; Erez, Neta ; Goldfinger, Naomi ; Rotter, Varda
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2004-07, Vol.23 (34), p.5759-5769
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Amplification of the 20q Chromosomal Arm Occurs Early in Tumorigenic Transformation and May Initiate Cancer
Author / Creator:Tabach, Yuval ; Kogan-Sakin, Ira ; Buganim, Yosef ; Solomon, Hilla ; Goldfinger, Naomi ; Hovland, Randi ; Ke, Xi-Song ; Oyan, Anne M. ; Kalland, Karl-H. ; Rotter, Varda ; Domany, Eytan
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-01, Vol.6 (1), p.e14632
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Showing 1 to 20 of 85 results

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When mutants gain new powers: news from the mutant p53 field

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Gain-of-Function Mutant p53: All the Roads Lead to Tumorigenesis

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p53 on the crossroad between regeneration and cancer

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Visual barcodes for clonal-multiplexing of live microscopy-based assays

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Capturing tumor complexity in vitro: Comparative analysis of 2D and 3D tumor models for drug discovery

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Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues

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Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers

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Diverse p53/DNA binding modes expand the repertoire of p53 response elements

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High Throughput Analysis of Golgi Structure by Imaging Flow Cytometry

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Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

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Pla2g16 phospholipase mediates gain-of-function activities of mutant p53

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TMPRSS2/ERG Promotes Epithelial to Mesenchymal Transition through the ZEB1/ZEB2 Axis in a Prostate Cancer Model

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p53 Plays a Role in Mesenchymal Differentiation Programs, in a Cell Fate Dependent Manner

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Global profiling of histone and DNA methylation reveals epigenetic-based regulation of gene expression during epithelial to mesenchymal transition in prostate cells

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Rescue of embryonic stem cells from cellular transformation by proteomic stabilization of mutant p53 and conversion into WT conformation

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TM7SF3, a novel p53-regulated homeostatic factor, attenuates cellular stress and the subsequent induction of the unfolded protein response

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Genome-Wide Profiling of Histone H3 Lysine 4 and Lysine 27 Trimethylation Reveals an Epigenetic Signature in Prostate Carcinogenesis

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On a fundamental structure of gene networks in living cells

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Activated p53 suppresses the histone methyltransferase EZH2 gene

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Amplification of the 20q Chromosomal Arm Occurs Early in Tumorigenic Transformation and May Initiate Cancer

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