Dabigatran versus Warfarin in Patients with Mechanical Heart Valves
Dabigatran versus Warfarin in Patients with Mechanical Heart Valves
About this item
Full title
Author / Creator
Eikelboom, John W , Connolly, Stuart J , Brueckmann, Martina , Granger, Christopher B , Kappetein, Arie P , Mack, Michael J , Blatchford, Jon , Devenny, Kevin , Friedman, Jeffrey , Guiver, Kelly , Harper, Ruth , Khder, Yasser , Lobmeyer, Maximilian T , Maas, Hugo , Voigt, Jens-Uwe , Simoons, Maarten L , Van de Werf, Frans and RE-ALIGN Investigators
Publisher
Waltham, MA: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
Waltham, MA: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
In a phase 2 trial, patients with mechanical heart valves were randomly assigned to receive either dabigatran or warfarin for anticoagulation. Dabigatran was associated with higher rates of ischemic stroke (5%, vs. 0% with warfarin) and major bleeding (4% vs. 2%).
Prosthetic heart-valve replacement is recommended for many patients with severe va...
Alternative Titles
Full title
Dabigatran versus Warfarin in Patients with Mechanical Heart Valves
Authors, Artists and Contributors
Author / Creator
Connolly, Stuart J
Brueckmann, Martina
Granger, Christopher B
Kappetein, Arie P
Mack, Michael J
Blatchford, Jon
Devenny, Kevin
Friedman, Jeffrey
Guiver, Kelly
Harper, Ruth
Khder, Yasser
Lobmeyer, Maximilian T
Maas, Hugo
Voigt, Jens-Uwe
Simoons, Maarten L
Van de Werf, Frans
RE-ALIGN Investigators
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1437581144
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1437581144
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1300615
