Immune self-reactivity triggered by drug-modified HLA-peptide repertoire
Immune self-reactivity triggered by drug-modified HLA-peptide repertoire
About this item
Full title
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The paper describes the mechanism by which small-molecule drugs such as abacavir affect antigen presentation and consequently T-cell response in immunologically based drug reactions such as abacavir hypersensitivity syndrome (AHS) and carbamazepine-induced Stevens–Johnson syndrome (SJS).
HLA target in self-immune drug reactions
Immunologicall...
Alternative Titles
Full title
Immune self-reactivity triggered by drug-modified HLA-peptide repertoire
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Record Identifier
TN_cdi_proquest_miscellaneous_1439225741
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1439225741
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature11147
