An interleukin-17–mediated paracrine network promotes tumor resistance to anti-angiogenic therapy
An interleukin-17–mediated paracrine network promotes tumor resistance to anti-angiogenic therapy
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New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
The efficacy of anti-angiogenic therapy for cancer could be improved if tumor resistance mechanisms were better understood. In this report, Napoleone Ferrara and his colleagues uncover a tumor resistance mechanism to VEGF-neutralizing antibodies triggered by IL-17, the hallmark cytokine of T
H
17 cells.
Although angiogenesis inhibitors hav...
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Full title
An interleukin-17–mediated paracrine network promotes tumor resistance to anti-angiogenic therapy
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TN_cdi_proquest_miscellaneous_1439234621
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1439234621
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.3291
