Clonal allelic predetermination of immunoglobulin-κ rearrangement
Clonal allelic predetermination of immunoglobulin-κ rearrangement
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London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
Immunoglobulin genes are expressed from either the maternal or paternal chromosome; it is now shown that in early haematopoietic stem cells, an individual cell can choose either of the two alleles, but as they develop they become committed to only one.
Alternative paths for stem cells
Most of the genome is expressed biallelically — that is, w...
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Full title
Clonal allelic predetermination of immunoglobulin-κ rearrangement
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TN_cdi_proquest_miscellaneous_1439238474
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1439238474
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature11496
