A nuclear F-actin scaffold stabilizes ribonucleoprotein droplets against gravity in large cells
A nuclear F-actin scaffold stabilizes ribonucleoprotein droplets against gravity in large cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Actin is abundant in the nuclei of oocytes but its role has been unclear. Feric and Brangwynne find that actin forms a network that prevents the sedimentation of RNA and protein bodies caused by gravitational forces.
The size of a typical eukaryotic cell is of the order of ∼10 μm. However, some cell types grow to very large sizes, including oocy...
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A nuclear F-actin scaffold stabilizes ribonucleoprotein droplets against gravity in large cells
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TN_cdi_proquest_miscellaneous_1443398744
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1443398744
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb2830
