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HLA-B13:01 and the Dapsone Hypersensitivity Syndrome

HLA-B13:01 and the Dapsone Hypersensitivity Syndrome

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1445911069

Publication information

Publisher

Waltham, MA: Massachusetts Medical Society

More information

Scope and Contents

Contents

Dapsone is an important medication for the treatment of leprosy, but a life-threatening drug hypersensitivity syndrome develops in some patients. In this report from China, an
HLA-B
locus is identified as a strong genetic risk factor for the syndrome.
Dapsone (4-4′-sulfonyldianiline), which was first synthesized in 1908,
1
is both an...

Alternative Titles

Full title

HLA-B13:01 and the Dapsone Hypersensitivity Syndrome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1445911069

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1445911069

Other Identifiers

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMoa1213096

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